3-tert-Butoxycarbonylamino-piperidine-1-carboxylic acid benzyl ester
Benzyl 3-(tert-butoxycarbonylamino)-piperidine-1-carboxylate
CAS: 406213-47-6
Molecular Formula: C18H26N2O4
3-tert-Butoxycarbonylamino-piperidine-1-carboxylic acid benzyl ester - Names and Identifiers
3-tert-Butoxycarbonylamino-piperidine-1-carboxylic acid benzyl ester - Physico-chemical Properties
| Molecular Formula | C18H26N2O4 |
| Molar Mass | 334.41 |
| Density | 1.15±0.1 g/cm3(Predicted) |
| Boling Point | 471.9±44.0 °C(Predicted) |
| pKa | 12.25±0.20(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD09952600 |
3-tert-Butoxycarbonylamino-piperidine-1-carboxylic acid benzyl ester - Introduction
Benzyl 3-(tert-butoxycarbonylamino)-piperidine-1-carboxylate is an organic compound with the chemical formula C20H28N2O4.
Nature:
-Appearance: colorless or light yellow liquid;
-Molecular weight: 364.45g/mol;
-Melting point: No data;
-Boiling point: no data;
-Density: No data;
-Solubility: Soluble in organic solvents such as methanol, dichloromethane, etc.
Use:
- Benzyl 3-(tert-butoxycarbonylamino)-piperidine-1-carboxylate is often used as an organic synthesis reagent and is widely used in the field of pharmaceutical synthesis and organic synthesis;
-It can be used to synthesize various compounds with biological activity, such as drugs, antibacterial agents, pesticides, etc;
-It can also be used as an intermediate for the synthesis of other organic compounds.
Preparation Method:
Benzyl 3-(tert-butoxycarbonylamino)-piperidine-1-carboxylate has many preparation methods, and the commonly used methods include the following steps:
1. Taking piperidine-1-carboxylic acid and tert-butyl alcohol ester condensation reaction to synthesize tert-butyl ester;
2. The tert-butyl ester reacts with Boc-ONH4 (tert-butyl hydroxyformyl amino) to generate 3-(tert-butoxycarbonylamino) piperidine -1-acid;
3. 3-(tert-butoxycarbonylamino) piperidine -1-acid reacts with benzyl alcohol to generate the target product.
Safety Information:
There is no detailed data on the safety of Benzyl 3-(tert-butoxycarbonylamino)-piperidine-1-carboxylate. Therefore, it is recommended to follow laboratory safety practices, wear appropriate personal protective equipment, and avoid contact with skin, eyes and respiratory tract. At the same time, pay attention to fire and explosion prevention during use and storage, and keep away from heat sources and flames. If you intend to use this compound, it is recommended to refer to the relevant literature and materials for more detailed safety information.
Nature:
-Appearance: colorless or light yellow liquid;
-Molecular weight: 364.45g/mol;
-Melting point: No data;
-Boiling point: no data;
-Density: No data;
-Solubility: Soluble in organic solvents such as methanol, dichloromethane, etc.
Use:
- Benzyl 3-(tert-butoxycarbonylamino)-piperidine-1-carboxylate is often used as an organic synthesis reagent and is widely used in the field of pharmaceutical synthesis and organic synthesis;
-It can be used to synthesize various compounds with biological activity, such as drugs, antibacterial agents, pesticides, etc;
-It can also be used as an intermediate for the synthesis of other organic compounds.
Preparation Method:
Benzyl 3-(tert-butoxycarbonylamino)-piperidine-1-carboxylate has many preparation methods, and the commonly used methods include the following steps:
1. Taking piperidine-1-carboxylic acid and tert-butyl alcohol ester condensation reaction to synthesize tert-butyl ester;
2. The tert-butyl ester reacts with Boc-ONH4 (tert-butyl hydroxyformyl amino) to generate 3-(tert-butoxycarbonylamino) piperidine -1-acid;
3. 3-(tert-butoxycarbonylamino) piperidine -1-acid reacts with benzyl alcohol to generate the target product.
Safety Information:
There is no detailed data on the safety of Benzyl 3-(tert-butoxycarbonylamino)-piperidine-1-carboxylate. Therefore, it is recommended to follow laboratory safety practices, wear appropriate personal protective equipment, and avoid contact with skin, eyes and respiratory tract. At the same time, pay attention to fire and explosion prevention during use and storage, and keep away from heat sources and flames. If you intend to use this compound, it is recommended to refer to the relevant literature and materials for more detailed safety information.
Last Update：2024-04-09 21:11:58
